Arlak Biotech Pvt.Ltd.
Arlak Biotech Pvt.Ltd. SCO 1,Wadhwa Nagar, Near Hotel Sun park,Kalka Highway , Zirakpur , Punjab , ( 140603 ) India
Product Details:
Product Type: Tablets
Brand Name: Arlak Biotech
Packaging Type Strip
Packaging: 10*6
Composition / Material Type: Drotaverine Hydrochloride & Mefenamic acid Tablets
Usages: NA
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SPADSPAS

COMPOSITION: - DROTAVERINE 80 MG + MEFENAMIC ACID 250 MG

PACKING: - 10X10

M.R.P: - 750

Drotaverine is an effective spasmolytic drug.

Mechanism of Action of Drotaverine

Drotaverine has spasmolytic and vasodilating action. It exerts its action by inhibiting phosphodiesterase enzyme IV. This will leads to a decrease in cyclic AMP level and reduction in calcium ions (Ca2+). The reduction of calcium ions will dilates the unstipped muscles and blood vessels strongly and relieves spasm of smooth muscles.

Pharmacokinets of Drotaverine

Absorption: Drotaverine is rapidly absorbed after oral administration.

Distribution: It is widely distributed in protein bound form.

Metabolism: Extensively metabolised in the liver.

Excretion: It is excreted mainly with the bile. Onset of Action for Drotaverine: -30 minutes

Duration of Action for Drotaverine : -4 hours.

Half Life of Drotaverine: -7 - 12 hours

Mechanism of Action of Mefenamic Acid

Mefenamic acid has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other analgesics. Mefenamic acid inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions.

Pharmacokinets of Mefenamic Acid

Absorption: Mefenamic acid is well absorbed after oral administration.

Distribution: It is distributed in the body in protein bound form.

Metabolism: It is metabolised in the liver.

Excretion: Mefenamic acid and its metabolites are excreted mainly in the urine.

Onset of Action for Mefenamic Acid: - 1-2 hours.

Duration of Action for Mefenamic Acid: -6 hours.

Half Life of Mefenamic Acid: -2-4 hours.

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